If you’re considering Spravato® (esketamine) treatment for depression, finding the right clinic in New York City can feel overwhelming — so we’ve rounded up the top 10 clinics to make your search easier.
1. Being Health - Editor’s Pick
- Address: 11 Hanover Sq, 18th Fl, New York, NY 10005 (Lower Manhattan); additional site in Williamsburg, Brooklyn
- Website: beinghealth.co/spravato
- Why it stands out: Psychiatrist-led Spravato program inside a modern, calming clinic; integrated psychiatry, psychotherapy, acupuncture & nutrition under one roof; in-network with major NYC plans (UnitedHealthcare, Aetna, Cigna, Northwell Direct, Oscar,); Lower Manhattan site purpose-built for Spravato monitoring (optional Wavepaths audio experience).
2. Mount Sinai – Depression & Anxiety Center (TRD Program)
- Address: 1399 Park Ave, New York, NY 10029
- Website: mountsinai.org (Depression & Anxiety Center)
- Why it stands out: Academic TRD program offering intranasal esketamine with full medical oversight; early NYC academic adopter; streamlined consult + monitoring protocols.
3. ColumbiaDoctors – Treatment-Resistant Depression Program
- Address: 630 W 168th St, New York, NY 10032
- Website: columbiadoctors.org (TRD Program)
- Why it stands out: Ivy-league program offering intranasal esketamine within a large academic system; access to research-informed care and subspecialists.
4. Principium Psychiatry
- Address: 110 E 42nd St, Suite 1810, New York, NY 10017 (Midtown); also Downtown at 26 Broadway, Suite 1103
- Website: principiumpsychiatry.com
- Why it stands out: Private practice with intranasal ketamine (Spravato) alongside IV ketamine & TMS; multiple Manhattan locations for convenience.
5. Nushama Wellness
- Address: 515 Madison Ave, 21st Fl, New York, NY 10022
- Website: nushama.com
- Why it stands out: Offers Spravato in addition to ketamine services in a serene, spa-like setting; central Midtown address.
6. Stella Mental Health (Stella Center – New York)
- Address: 137 E 25th St, 11th Fl, New York, NY 10010
- Website: stellamentalhealth.com
- Why it stands out: Multimodal interventional clinic featuring Spravato, ketamine infusions, and stellate ganglion block (SGB); trauma-informed care model.
7. Keta Medical Center (KetaMC)
- Address: 6 E 39th St, Suite 600, New York, NY 10016 (Midtown); also 7 W 96th St, Suite 1H (Upper West Side)
- Website: ketamc.com
- Why it stands out: Spravato offered alongside IV ketamine; extended evening/weekend hours; assists with insurance and prior authorization for Spravato.
8. Curated Mental Health
- Address: 253 W 28th St, 6th Fl, New York, NY 10001 (Chelsea); also 402 Metropolitan Ave, Brooklyn
- Website: curatedmentalhealth.com/spravato
- Why it stands out: Spravato program with clear patient education; accepts Cigna, Aetna, and UnitedHealthcare for Spravato/TMS/med-management; multiple NYC locations.
9. Elevate Medical — Certified Spravato Treatment Center
- Address: 336 W 37th St, Suite 1440, New York, NY 10018
- Website: elevatemedical.org/spravato-treatment-center-manhattan-ny
- Why it stands out: Certified Spravato center in Midtown with psychiatrist-led care and clear intake pathway; publishes Spravato guidance and updates.
10. Northwell Health — Zucker Hillside Hospital (Interventional Psychiatry)
- Address: 75-59 263rd St, Glen Oaks, NY 11004 (Queens)
- Website: northwell.edu/behavioral-health/treatments/ketamine
- Why it stands out: Large academic hospital program offering ketamine & esketamine in a supervised setting; interventional psychiatry team and hospital resources on site.
Next Steps
Spravato offers a new path forward for patients who haven’t found relief with traditional antidepressants. While every patient’s experience is unique, the research and real-world outcomes are promising.
For more personalized answers and to learn if Spravato is right for you, schedule a consultation with Being Health today or give us a call at 888-668-7600.
